Astrophysicist: Jones is my name. [Shakes Dr. Peters' hand] I'm in insurance.

Dr. Kathryn Railly: You had a bullet from World War I in your leg, James! How did it get there?

Dr. Peters: I think, Dr. Railly, you have given your "alarmists" a bad name. Surely there is very real and very convincing data that the planet cannot survive the excesses of the human race: proliferation of atomic devices, uncontrolled breeding habits, the rape of the environment, the pollution of land, sea, and air. In this context, isn't it obvious that "Chicken Little" represents the sane vision and that Homo Sapiens' motto, "Let's go shopping!" is the cry of the true lunatic?

Jose: I gotta fight 'em! I gotta fight 'em! you gotta help me fight 'em!

Louie: Science ain't an exact science with these clowns, but they're getting better.

Man: They find us through our teeth!

Thug: Stick around, bitch!

Wallace: Hey... is that the cops? I'm an innocent victim in here! I was attacked by a coked up whore and a — a fuckin' crazy dentist!

Dr. Kathryn Railly: Where are we going?
James Cole: Philadelphia.
Dr. Kathryn Railly: Philadelphia? That's more then a hundred miles away!
James Cole: I know, that's why I can't walk there.

Dr. Leland Goines: My God, Jeffrey. You truly are insane.
Jeffrey Goines: No, I'm not.

Dr. Owen Fletcher: You're a rational person. You're a trained psychiatrist. You know the difference between what's real and what's not.
Dr. Kathryn Railly: And what we say is the truth is what everybody accepts. Right, Owen? I mean, psychiatry: it's the latest religion. We decide what's right and wrong. We decide who's crazy or not. I'm in trouble here. I'm losing my faith.

James Cole: Look at them. They're just asking for it. Maybe the human race deserves to be wiped out.
Jeffrey Goines: Wiping out the human race? That's a great idea. That's great. But more of a long-term thing. I mean, first we have to focus on more immediate goals.

James Cole: She's not honey babe, She's a doctor. My psychiatrist. Understand?
Charlie the Hotel Clerk: Whatever gets it up for you, Jack.

James Cole: This is a place for crazy people. I'm not crazy.
Dr. Peters: We don't use the term "crazy," Mr. Cole.
James Cole: Well you've got some real nuts here.
Nobody is going to die! You're not going to save the world, Okay you're delusional. You've made this all up out of bits and pieces in your head...

James Cole: You're all gonna die.
Dr. Kathryn Railly: Nobody is going to die! You're not going to save the world, Okay your delusional. You've made this all up out of bits and pieces in you're head.
James Cole: No.
Dr. Kathryn Railly: Uh, Yes! Let me give you an example. You know Jeffrey Goines. You were both patients at County Hospital, at the same time.
James Cole: Jeffrey Goines was a fruitcake.