Hancock: That's a good meatball, boy.
Mary: Aaron.
Hancock: Momma's callin you.
Mary: No, his name's Aaron.

Hancock: You and I...
Mary: You and I what?
Hancock: We're the same.
Mary: No. I'm stronger.
Hancock: Really?
Mary: Oh, yeah.
Hancock: Who are we?
Mary: Gods. Angels. Different cultures call us by different names. Now all of a sudden it's "superhero."
Hancock: Are there more of us?
Mary: There were. They all died. It's just the two of us.

Large man: That woman could have been killed, she should sue you!
Crowd: Yeah!
Hancock: Okay, well you should sue McDonald's 'cause they fucked you up.
Woman: And I can smell that liquor in your breath!
Hancock: 'Cause I been drinkin', bitch!

Mary: I've lived for a very long time with Ray, and the one thing I learned — fate doesn't decide everything. People get to choose.
Hancock: And you chose to let me think I was here alone.
Mary: I didn't think you'd miss what you didn't remember.

Mary: We're becoming mortal. It's us, being close to each other. It never happened this fast before. You have to leave. The further you get from me, the better you're going to feel. You'll start getting your powers back — and be flying and breaking things and saving people before you know it. It's like I said. We were built in pairs, and when we get close to our opposites, we lose our power.
Hancock: Why?
Mary: So we can live human lives. Love. Connect. Grow old. Die.

Ray: Stop pretending that you do not care! You have a calling. You're a hero, Hancock. You're going to be miserable the rest of your life until you accept that. Trust me. Trust this plan, this process — you're staying here. When they call, a hero is what we're going to give them.
Hancock: How we going to do that, Ray?

Ray: We at Embrey Publicity would like to offer you the AllHeart symbol. Now you would be among a very select group of corporate giants to bear this logo on your product. And what this would say to the public is that your company, Pharmatopsis, had made a radical contribution to helping our world. And here is all you'd have to do to qualify: Your new TB drug, micadin, we would like you to give that product away, for free.
Businessman: Did you say free?
Ray: I did — only to those who really need it. Only to those who without it would otherwise die.
Businessman: Alright. As a concept "free" is kind of up there with "lethal side effects—"
Businessman 2: "Mandatory product recall."
Businessman: "Get indicted, going to jail —"
Businessman 2: "Get out, work at IHOP the rest of your career—"
Ray: Understandable reactions — a radical concept — but it is the brand that represents a fairer and better world. The brand that everyone is talking about. ... Anyway — we can save the world. Someone's just got to go first. What do you say?
CEO: Are you a crackpot?

NOT okay. After Hancock throws a young boy high into the sky for calling him an asshole.

Technically speaking, he's my husband. About Hancock

All you people blocking the intersection...you're all idiots. Statement to the people at the train tracks.

Call me an asshole, one more time. Statement made to a small boy who is calling him an asshole, and later to a hostage taker.

Call me crazy — one more time... After Hancock calls her crazy during an argument.

Cause I been drinkin', bitch! Statement to a woman who complains that Hancock smells like liquor.

Do I look like I care what people think? Statement to Ray Embrey who is trying to convince him he needs his help as a public relations manager (this appears in the trailers only, not in the theatrical release of the movie).

Good Job. Statement to a police officer fighting some hostage takers.